THE PUMMERER CYCLIZATION ROUTE TO THE IBOPHYLLIDINE ALKALOIDS - TOTAL SYNTHESIS OF (+/-)-DEETHYLIBOPHYLLIDINE

被引：32

作者：

CATENA, J ^{[1
]}

VALLS, N ^{[1
]}

BOSCH, J ^{[1
]}

BONJOCH, J ^{[1
]}

机构：

[1] UNIV BARCELONA,FAC PHARM,ORGAN CHEM LAB,E-08028 BARCELONA,SPAIN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(00)73377-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pummerer cyclization of beta-aminoethyl sulfoxide 6 was effectively achieved using TFAA-TFA in toluene at 80 degrees C. The cyclized product 7 was then converted to the alkaloid deethylibophyllidine. The required pyrrolo[3,2-c]carbazole 6 was prepared in five steps from 4-methoxyphenethylamine.

引用

页码：4433 / 4436

页数：4

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