ENKEPHALIN PSEUDOPEPTIDES - RESISTANCE TO INVITRO PROTEOLYTIC DEGRADATION AFFORDED BY AMIDE BOND REPLACEMENTS EXTENDS TO REMOTE SITES

被引：33

作者：

BENOVITZ, DE ^{[1
]}

SPATOLA, AF ^{[1
]}

机构：

[1] UNIV LOUISVILLE,DEPT CHEM,LOUISVILLE,KY 40292

来源：

PEPTIDES | 1985年 / 6卷 / 02期

关键词：

D O I：

10.1016/0196-9781(85)90049-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：257 / 261

页数：5

共 20 条

[1] A RAPID NON-ACIDOLYTIC METHOD FOR DEPROTECTION AND REMOVAL OF PEPTIDES FROM SOLID-PHASE RESINS - APPLICATIONS OF AMMONIUM FORMATE CATALYTIC TRANSFER HYDROGENATION [J].

ANWER, MK ;

SPATOLA, AF .

TETRAHEDRON LETTERS, 1981, 22 (44) :4369-4372

[2] PARTIALLY MODIFIED RETRO-INVERSO-ENKEPHALINAMIDES - TOPOCHEMICAL LONG-ACTING ANALOGS INVITRO AND INVIVO [J].

CHOREV, M ;

SHAVITZ, R ;

GOODMAN, M ;

MINICK, S ;

GUILLEMIN, R .

SCIENCE, 1979, 204 (4398) :1210-1212

[3] INCORPORATION OF TRANS-OLEFINIC DIPEPTIDE ISOSTERES INTO ENKEPHALIN AND SUBSTANCE-P ANALOGS [J].

COX, MT ;

GORMLEY, JJ ;

HAYWARD, CF ;

PETTER, NN .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1980, (17) :800-802

[4] SYNTHESIS AND OPIOID ACTIVITIES OF STEREOISOMERS AND OTHER D-AMINO-ACID ANALOGS OF METHIONINE-ENKEPHALIN [J].

COY, DH ;

KASTIN, AJ ;

SCHALLY, AV ;

MORIN, O ;

CARON, NG ;

LABRIE, F ;

WALKER, JM ;

FERTEL, R ;

BERNTSON, GG ;

SANDMAN, CA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1976, 73 (03) :632-638

[5] A CYCLIC ENKEPHALIN ANALOG WITH HIGH INVITRO OPIATE ACTIVITY [J].

DIMAIO, J ;

SCHILLER, PW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (12) :7162-7166

[6] LC-EC OF ENDORPHINS [J].

FLEMING, LH ;

REYNOLDS, NC .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1984, 7 (04) :793-808

[7] INVIVO EVALUATION OF THE OPIATE DELTA RECEPTOR ANTAGONIST ICI 154,129 [J].

GORMLEY, JJ ;

MORLEY, JS ;

PRIESTLEY, T ;

SHAW, JS ;

TURNBULL, MJ ;

WHEELER, H .

LIFE SCIENCES, 1982, 31 (12-1) :1263-1266

[8] MODE OF DEACTIVATION OF ENKEPHALINS BY RAT AND HUMAN-PLASMA AND RAT-BRAIN HOMOGENATES [J].

HAMBROOK, JM ;

MORGAN, BA ;

RANCE, MJ ;

SMITH, CFC .

NATURE, 1976, 262 (5571) :782-783

[9] DOUBLE-BOND ISOSTERES OF THE PEPTIDE-BOND - ENKEPHALIN ANALOG [J].

HANN, MM ;

SAMMES, PG ;

KENNEWELL, PD ;

TAYLOR, JB .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1980, (05) :234-235

[10] ELECTROCHEMICAL INVESTIGATIONS OF AMINO-ACIDS AT SOLID ELECTRODES .2. AMINO-ACIDS CONTAINING NO SULFUR-ATOMS - TRYPTOPHAN, TYROSINE, HISTIDINE AND DERIVATIVES [J].

MALFOY, B ;

REYNAUD, JA .

JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1980, 114 (02) :213-223

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