SYNTHESIS OF (+)-FRAGOLIDE AND (-)-PERENIPORIN-B VIA VINYLSILANE TERMINATED CATIONIC CYCLIZATION

被引：37

作者：

BURKE, SD ^{[1
]}

SHANKARAN, K ^{[1
]}

HELBER, MJ ^{[1
]}

机构：

[1] UNIV S CAROLINA,DEPT CHEM,COLUMBIA,SC 29208

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 36期

关键词：

VINYLSILANE-MEDIATED CATIONIC BICYCLIZATION; DRIMANE SESQUITERPENE SYNTHESIS, [3,3] AND [2,3] SIGMATROPIC REARRANGEMENTS; SULFUR-TO-CARBON STEREOGENICITY TRANSFER;

D O I：

10.1016/S0040-4039(00)92273-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantioselective syntheses of (+)-fragolide and (-)-pereniporin B are detailed. Marino's lactone annulation method was employed to establish relative and absolute stereochemistry at carbon in the bicyclization substrate. Regio- and stereoselective oxidations of tricyclic drimane precursors are described.

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页码：4655 / 4658

页数：4

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