SELF-HEALING JUVENILE CUTANEOUS MUCINOSIS IN A PATIENT WITH NEPHROBLASTOMA

Self-healing juvenile cutaneous mucinosis is characterized by an early age of onset, the presence of plaques and nodules in a characteristic distribution, and rapid onset followed by spontaneous resolution of the lesions within a period of weeks to months. Only four previous cases have been reported. The patient in this study was an 8-year-old child who developed cutaneous lesions characteristic of self-healing juvenile cutaneous mucinosis while undergoing chemotherapy for a nephroblastoma. This is the first case described of self-healing juvenile cutaneous mucinosis associated with a neoplasm. Self-healing juvenile cutaneous mucinosis has recently been recognized as a new entity distinct from the previously described forms of cutaneous mucinosis.(1) So far only four cases have been reported.(1-3) The criteria for the diagnosis as defined by Bonerandi et nl. in 1980(1) include early age of onset, the presence of plaques and nodules in a characteristic distribution and rapid onset followed by spontaneous resolution of the lesions within a period of weeks to months. The absence of paraproteinaemia, bone marrow plasmacytosis and thyroid dysfunction are additional features which help to distinguish this condition from other forms of cutaneous mucinosis. We report a case of self-healing juvenile cutaneous mucinosis which developed in a child undergoing chemotherapy for a stage III nephroblastoma.