SEROLOGY AND ANTHRAX IN HUMANS, LIVESTOCK AND ETOSHA-NATIONAL-PARK WILDLIFE

被引:69
作者
TURNBULL, PCB
DOGANAY, M
LINDEQUE, PM
AYGEN, B
MCLAUGHLIN, J
机构
[1] ERCIYES UNIV,FAC MED,INFECT DIS SECT,KAYSERI 38039,TURKEY
[2] STATE VET SERV,NOTTINGHAM NG8 3SN,ENGLAND
关键词
D O I
10.1017/S0950268800049773
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Results are presented from a number of epidemiological studies using enzyme immunoassays (EIA) based on the purified anthrax toxin antigens, protective antigen, lethal factor and oedema factor. Studies on sera from a group of 62 human anthrax patients in Turkey and from cattle in Britain following two unrelated outbreaks of anthrax show that EIA using protective antigen can be a useful diagnostic aid and will detect subclinical infections in appropriate circumstances. A serological survey on wildlife in the Etosha National Park, Namibia, where anthrax is endemic, showed that naturally acquired anthrax-specific antibodies are rare in herbivores but common in carnivores; in carnivores, titres appear to reflect the prevalence of anthrax in their ranges. Problems, as yet unresolved, were encountered in studies on sera from pigs following an outbreak of anthrax on a farm in Wales. Clinical details, including treatment, of the human and one of the bovine outbreaks are summarized and discussed in relation to the serological findings.
引用
收藏
页码:299 / 313
页数:15
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