PULMONARY VASCULAR REACTIVITY IN SEVERE PULMONARY-HYPERTENSION ASSOCIATED WITH MIXED CONNECTIVE-TISSUE DISEASE

被引：10

作者：

JOLLIET, P

THORENS, JB

CHEVROLET, JC

机构：

[1] UNIV HOSP GENEVA,MED INTENS CARE UNIT,GENEVA,SWITZERLAND

[2] UNIV HOSP GENEVA,DIV PNEUMOL,GENEVA,SWITZERLAND

来源：

THORAX | 1995年 / 50卷 / 01期

关键词：

PULMONARY VASCULAR REACTIVITY; PULMONARY HYPERTENSION; MIXED CONNECTIVE TISSUE DISEASE; NITRIC OXIDE;

D O I：

10.1136/thx.50.1.96

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Pulmonary vascular reactivity tests were performed in a young woman with mixed connective tissue disease and severe pulmonary hypertension. Vasoreactivity was documented in response to intravenous prostacyclin (PGI(2)), oral nifedipine, and inhaled nitric oxide, with quantitative differences. Nitric oxide produced a moderate lowering of pulmonary arterial pressure and resistance without any deleterious systemic effect. The use of nitric oxide in testing for pulmonary vasoreactivity merits further evaluation.

引用

页码：96 / 97

页数：2

共 9 条

[1] ACUTE AND LONG-TERM EFFECTS OF NIFEDIPINE ON PULMONARY AND SYSTEMIC HEMODYNAMICS IN PATIENTS WITH PULMONARY-HYPERTENSION ASSOCIATED WITH DIFFUSE SYSTEMIC-SCLEROSIS, THE CREST SYNDROME AND MIXED CONNECTIVE-TISSUE DISEASE [J].