NUCLEOPHILIC TRAPPING OF 7,11-DIDEOXYANTHRACYCLINONE QUINONE METHIDES

被引：37

作者：

RAMAKRISHNAN, K ^{[1
]}

FISHER, J ^{[1
]}

机构：

[1] UNIV MINNESOTA,DEPT CHEM,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1983年 / 105卷 / 24期

关键词：

D O I：

10.1021/ja00362a037

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：7187 / 7188

页数：2

共 12 条

[1] NADPH CYTOCHROME-P-450 REDUCTASE ACTIVATION OF QUINONE ANTI-CANCER AGENTS TO FREE-RADICALS [J].

BACHUR, NR ;

GORDON, SL ;

GEE, MV ;

KON, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (02) :954-957

[2] CONVENIENT AB-RING SEGMENTS FOR ANTHRACYCLINONE SYNTHESIS VIA BISHYDROXYLATION OF 2-ETHYL-5,8-DIMETHOXY-7-BROMO-1-TETRALONE [J].

COBURN, CE ;

ANDERSON, DK ;

SWENTON, JS .

JOURNAL OF ORGANIC CHEMISTRY, 1983, 48 (09) :1455-1461

[3] DIRECT ENZYME-CATALYZED REDUCTION OF ANTHRACYCLINES BY REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE [J].

FISHER, J ;

RAMAKRISHNAN, K ;

BECVAR, JE .

BIOCHEMISTRY, 1983, 22 (06) :1347-1355

[4]

FISHER J, UNPUB BIOCHEMISTRY

[5] ELECTROPHILIC TRAPPING OF THE TAUTOMER OF 7-DEOXYDAUNOMYCINONE - A POSSIBLE MECHANISM FOR COVALENT BINDING OF DAUNOMYCIN TO DNA [J].

KLEYER, DL ;

KOCH, TH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (15) :5154-5155

[6] SPECTROSCOPIC OBSERVATION OF THE TAUTOMER OF 7-DEOXYDAUNOMYCINONE FROM ELIMINATION OF DAUNOSAMINE FROM DAUNOMYCIN HYDROQUINONE [J].

KLEYER, DL ;

KOCH, TH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (08) :2504-2505

[7] PROPOSED REACTION-MECHANISM FOR THE ENZYMATIC REDUCTIVE CLEAVAGE OF GLYCOSIDIC BOND IN ANTHRACYCLINE ANTIBIOTICS [J].

KOMIYAMA, T ;

OKI, T ;

INUI, T .

JOURNAL OF ANTIBIOTICS, 1979, 32 (11) :1219-1222

[8] NATURALLY-OCCURRING QUINONES AS POTENTIAL BIOREDUCTIVE ALKYLATING-AGENTS [J].

MOORE, HW ;

CZERNIAK, R .

MEDICINAL RESEARCH REVIEWS, 1981, 1 (03) :249-280

[9]

PRAIRIE M, 1983, COMMUNICATION 0525

[10] SYNTHETIC APPROACHES TO ADRIAMYCIN - DEGRADATION OF DAUNORUBICIN TO NON-ASYMMETRIC TETRACYCLIC KETONE AND REFUNCTIONALIZATION OF A-RING TO ADRIAMYCIN [J].

SMITH, TH ;

FUJIWARA, AN ;

HENRY, DW ;

LEE, WW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (07) :1969-1971

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