WHOLE-BOWEL IRRIGATION AS TREATMENT FOR ZINC-SULFATE OVERDOSE

被引:22
作者
BURKHART, KK [1 ]
KULIG, KW [1 ]
RUMACK, B [1 ]
机构
[1] UNIV COLORADO,HLTH SCI CTR,ROCKY MT POISON & DRUG CTR,645 BANNOCK ST,DENVER,CO 80204
关键词
whole-bowel irrigation; zinc sulfate; overdose;
D O I
10.1016/S0196-0644(05)81523-9
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A 16-year-old boy ingested approximately 50 zinc sulfate tablets (ZnSO4; 500-mg tablets). After spontaneous emesis, ipecac-induced emesis, and orogastric lavage, an abdominal radiograph performed four hours after ingestion still demonstrated approximately 50 ZnSO4 tablets within the stomach and three pills within the colon. Whole-bowel irrigation was begun with a polyethylene glycol lavage solution (PEG; Golytely®) that was administered through a nasogastric tube; within one hour, the patient began producing a rectal effluent that contained pills. The patient remained asymptomatic throughout whole-bowel irrigation. Stool guaiac tests were negative. The serum chloride, however, increased from 105 to 127 mEq/L. Follow-up kidney, ureter, and bladder studies demonstrated the clearance of the zinc tablets from the gastrointestinal tract during the next 24 hours. © 1990 American College of Emergency Physicians.
引用
收藏
页码:1167 / 1170
页数:4
相关论文
共 26 条
[1]  
Okonek, Hofmann, Henningsen, Efficacy of gut lavage, hemodialysis, and hemoperfusion in the therapy of paraquat or diquat intoxication, Arch Toxicol, 36, pp. 43-51, (1976)
[2]  
Tenenbein, Whole bowel irrigation as a gastrointestinal decontamination procedure after acute poisoning, Med Toxicol, 3, pp. 77-84, (1988)
[3]  
Tenebein, Whole bowel irrigation in iron poisoning, The Journal of Pediatrics, 111, pp. 142-145, (1987)
[4]  
Tenenbein, Whole bowel irrigation for toxic ingestions, Clin Toxicol, 23, pp. 177-184, (1985)
[5]  
Tenenbein, Cohen, Sitar, Whole bowel irrigation as a decontamination procedure after acute drug overdose, Arch Intern Med, 147, pp. 905-907, (1987)
[6]  
Rosenberg, Livingstone, McLellan, Effect of whole-bowel irrigation on the antidotal efficacy of oral activated charcoal, Ann Emerg Med, 17, pp. 681-683, (1988)
[7]  
Brown, Becker, Olson, Et al., Whole gut lavage in a simulated drug overdose, Vet Hum Toxicol, 29, (1987)
[8]  
Stephenson, Zinc phosphide poisoning, Arch Environ Health, 15, pp. 83-88, (1967)
[9]  
Chobanian, Accidental ingestion of liquid zinc chloride: Local and systemic effects, Ann Emerg Med, 10, pp. 91-93, (1981)
[10]  
Moore, Bleeding gastric erosion after oral zinc sulphate, Br Med J, 1, (1978)