THE GLYCOSOMES OF THE KINETOPLASTIDA

被引：38

作者：

OPPERDOES, FR

MICHELS, PAM

机构：

[1] Research Unit for Tropical Diseases, International Institute of Cellular and Molecular Pathology, B-1200 Brussels

来源：

BIOCHIMIE | 1993年 / 75卷 / 3-4期

关键词：

GLYCOSOMES; KINETOPLASTIDA; PEROXISOMES; GLYCOLYTIC ENZYMES;

D O I：

10.1016/0300-9084(93)90081-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glycosomes are the microbodies of the organisms belonging to the order of the Kinetoplastida, comprising trypanosomes and leishmanias, both pathogens to man. The organelles sequester a number of glycolytic enzymes that are normally located in the cytosol in other eukaryotic organisms, and share some enzymes with peroxisomes and glyoxysomes of other protists, plants and animals. Proteins enter the glycosome by a mechanism of post-translational translocation which involves in some, but not all, cases a C-terminal oligopeptide sequence.

引用

页码：231 / 234

页数：4

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