DIRECTED METALATION AND NEW SYNTHETIC TRANSFORMATIONS OF 5-ARYLTETRAZOLES

被引：47

作者：

FLIPPIN, LA

机构：

[1] Syntex Research, Institute of Organic Chemistry, Palo Alto, CA 94304

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 47期

关键词：

D O I：

10.1016/0040-4039(91)80425-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The tetrazole moiety is a useful directing group for the lithiation of 5-aryl substituents. Dilithiated 5-aryltetrazoles generally react with alkyl halides and aldehydes to give substitution and addition products, respectively.

引用

页码：6857 / 6860

页数：4

共 14 条

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