学术探索
学术期刊
新闻热点
数据分析
智能评审

THE PHARMACOKINETICS AND PHARMACODYNAMICS OF DILTIAZEM AND ITS METABOLITES IN HEALTHY-ADULTS AFTER A SINGLE ORAL DOSE

被引：53
作者：
BOYD, RA
CHIN, SK
DONPEDRO, O
VEROTTA, D
SHEINER, LB
WILLIAMS, RL
GIACOMINI, KM
机构：
[1] UNIV CALIF SAN FRANCISCO, SCH PHARM, DEPT PHARM, S-926, SAN FRANCISCO, CA 94143 USA
[2] UNIV CALIF SAN FRANCISCO, SCH MED, DEPT LAB MED, SAN FRANCISCO, CA 94143 USA
[3] UNIV CALIF SAN FRANCISCO, SCH MED, DIV CLIN PHARMACOL, SAN FRANCISCO, CA 94143 USA
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 1989年 / 46卷 / 04期
关键词：
D O I：
10.1038/clpt.1989.159
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：408 / 419
页数：12
相关论文
共 40 条
  • [1] Akaike H., 1976, MATH SCI, V14, P5
  • [2] SERUM BINDING OF DILTIAZEM IN HUMANS
    BLOEDOW, DC
    PIEPHO, RW
    NIES, AS
    GAL, J
    [J]. JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 22 (04) : 201 - 205
  • [3] RELATIONSHIPS BETWEEN HEART-RATE AND PR INTERVAL DURING PHYSIOLOGICAL AND PHARMACOLOGICAL INTERVENTIONS
    CARRUTHERS, SG
    MCCALL, B
    CORDELL, BA
    WU, R
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1987, 23 (03) : 259 - 265
  • [4] CAVERO I, 1979, NEW DRUG THERAPY CAL, P61
  • [5] NUMERICAL DECONVOLUTION BY LEAST-SQUARES - USE OF PRESCRIBED INPUT FUNCTIONS
    CUTLER, DJ
    [J]. JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1978, 6 (03): : 227 - 241
  • [6] EFFECTS OF SUSTAINED INTRAVENOUS DILTIAZEM INFUSION IN HEALTHY-PERSONS
    ELLENBOGEN, KA
    ROARK, SF
    SMITH, MS
    MCCARTHY, EA
    BJORNSSON, TD
    PRITCHETT, ELC
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1986, 58 (11) : 1055 - 1060
  • [7] PHARMACOKINETICS AND PHARMACODYNAMIC EFFECTS OF AQUEOUS DILTIAZEM IN HEALTHY HUMANS
    FU, M
    HUNG, JS
    YEH, SJ
    LIN, FC
    HSU, RS
    WU, D
    [J]. JOURNAL OF CLINICAL PHARMACOLOGY, 1987, 27 (02) : 106 - 110
  • [8] CORRECTION FOR VOLUME SHIFT DURING EQUILIBRIUM DIALYSIS BY MEASUREMENT OF PROTEIN-CONCENTRATION
    GIACOMINI, KM
    FEE, MW
    TOZER, TN
    [J]. PHARMACEUTICAL RESEARCH, 1984, (04) : 179 - 181
  • [9] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF DILTIAZEM AND 4 OF ITS METABOLITES IN PLASMA - APPLICATION TO PHARMACOKINETICS
    GOEBEL, KJ
    KOLLE, EU
    [J]. JOURNAL OF CHROMATOGRAPHY, 1985, 345 (02): : 355 - 363
  • [10] PHARMACOKINETICS OF DILTIAZEM AFTER INTRAVENOUS AND ORAL-ADMINISTRATION
    HERMANN, P
    RODGER, SD
    REMONES, G
    THENOT, JP
    LONDON, DR
    MORSELLI, PL
    [J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 24 (03) : 349 - 352
1234