AN IMPROVED PREPARATION OF AROMATASE INHIBITOR 4-HYDROXYANDROST-4-ENE-3,17-DIONE

被引：7

作者：

CIATTINI, PG

MORERA, E

ORTAR, G

机构：

[1] UNIV ROME LA SAPIENZA,CNR,DIPARTIMENTO STUDI FARMACEUT,I-00185 ROME,ITALY

[2] UNIV ROME LA SAPIENZA,CNR,CTR STUDIO CHIM FARM,I-00185 ROME,ITALY

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 13期

关键词：

D O I：

10.1080/00397919208021325

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compound has been prepared in 47% overall yield from androst-4-ene-3,17-dione (1) by a two-step sequence comprising hydrox-ylation of 1 with OsO4 / H2O2, followed by dehydration of the resultant diols 3 in alkaline medium.

引用

页码：1949 / 1952

页数：4

共 13 条

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