OXIRANYLLITHIUM REAGENTS - GENERATION FROM ORGANOTIN PRECURSORS, ADDITION TO ALDEHYDES AND KETONES, AND DIMERIZATION TO ALPHA,ALPHA'-DIALKOXYOLEFINS

被引：63

作者：

LOHSE, P ^{[1
]}

LONER, H ^{[1
]}

ACKLIN, P ^{[1
]}

STERNFELD, F ^{[1
]}

PFALTZ, A ^{[1
]}

机构：

[1] SWISS FED INST TECHNOL,ORGAN CHEM LAB,CH-8092 ZURICH,SWITZERLAND

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)74841-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxiranyllithium compounds can be generated from organotin precursors by tin-lithium exchange with butyllithium in THF at -90-degrees-C. In the presence of TMEDA, they react with aldehydes and ketones to give epoxy alcohols in good yields. In the absence of TMEDA, they dimerize to alpha,alpha'-dialkoxyolefins.

引用

页码：615 / 618

页数：4

共 19 条

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