CHROMOSOMAL ASSIGNMENTS OF 17 STRUCTURAL GENES AND 11 RELATED DNA FRAGMENTS IN RATS (RATTUS-NORVEGICUS) BY SOUTHERN BLOT ANALYSIS OF RAT X MOUSE SOMATIC-CELL HYBRID CLONES

被引：41

作者：

YASUE, M ^{[1
]}

SERIKAWA, T ^{[1
]}

KURAMOTO, T ^{[1
]}

MORI, M ^{[1
]}

HIGASHIGUCHI, T ^{[1
]}

ISHIZAKI, K ^{[1
]}

YAMADA, J ^{[1
]}

机构：

[1] KYOTO UNIV,CTR RADIAT BIOL,KYOTO 606,JAPAN

来源：

GENOMICS | 1992年 / 12卷 / 04期

关键词：

D O I：

10.1016/0888-7543(92)90290-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

DNA from 18 rat × mouse somatic cell hybrid clones, which segregated individual rat chromosomes, was analyzed by Southern blot for chromosomal gene assignments. Through the use of 17 DNA probes cloned from 7 rat genes, A2M, ATP1A1, ATP1A2, ATP1A3, B2M, GSTP, and SMST; 5 mouse genes, Ncam, Ngfg, Pim-1, Tcp-1, and Trp53; and 5 human genes, MBP, MYB, NEFM, SCN2A, and TCRGC1, 17 structural genes including 15 newly assigned genes and 11 related DNA fragments were assigned to particular rat chromosomes. Syntenic conservation of the genes among rats, mice, and humans is discussed. © 1992.

引用

页码：659 / 664

页数：6

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