FAMILY OF CYCLIC-NUCLEOTIDE GATED ION CHANNELS

被引：117

作者：

KAUPP, UB

机构：

[1] Institut für Biologische Informationsverarbeitung, Forschungszentrum Jülich, Leo Brandt Strasse

来源：

CURRENT OPINION IN NEUROBIOLOGY | 1995年 / 5卷 / 04期

关键词：

D O I：

10.1016/0959-4388(95)80002-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A variety of different cyclic nucleotide gated ion channels have recently been identified using molecular cloning and electrophysiological techniques. Current research is focussed on the specific molecular determinants that endow these channels with their distinctive character of gating, selectivity and modulation. In some cases, it has been possible to identify the specific physiological roles of different cyclic nucleotide gated channels. Their interactions with Ca2+ and calmodulin are particularly important, and determine the specific functions these channels subserve in distinct cells.

引用

收藏

页码：434 / 442

页数：9

相关论文

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