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5-SUBSTITUTED 2'-DEOXYURIDINES - CORRELATION BETWEEN INHIBITION OF TUMOR-CELL GROWTH AND INHIBITION OF THYMIDINE KINASE AND THYMIDYLATE SYNTHETASE

被引：120
作者：
BALZARINI, J
DECLERCQ, E
MERTES, MP
SHUGAR, D
TORRENCE, PF
机构：
[1] CATHOLIC UNIV LEUVEN, RIGA INST MED RES, B-3000 LOUVAIN, BELGIUM
[2] UNIV KANSAS, SCH PHARM, DEPT MED CHEM, LAWRENCE, KS 66045 USA
[3] ACAD SCI WARSZAWA, INST BIOCHEM & BIOPHYS, PL-02532 WARSZAWA, POLAND
[4] NIADDKD, CHEM LAB, BETHESDA, MD 20205 USA
来源：
BIOCHEMICAL PHARMACOLOGY | 1982年 / 31卷 / 22期
关键词：
D O I：
10.1016/0006-2952(82)90594-9
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：3673 / 3682
页数：10
相关论文
共 60 条
  • [1] ANSFIELD FJ, 1963, CANCER CHEMOTH REP, P101
  • [2] ROLE OF THYMIDINE KINASE IN THE INHIBITORY ACTIVITY OF 5-SUBSTITUTED-2'-DEOXYURIDINES ON THE GROWTH OF HUMAN AND MURINE TUMOR-CELL LINES
    BALZARINI, J
    DECLERCQ, E
    TORRENCE, PF
    MERTES, MP
    PARK, JS
    SCHMIDT, CL
    SHUGAR, D
    BARR, PJ
    JONES, AS
    VERHELST, G
    WALKER, RT
    [J]. BIOCHEMICAL PHARMACOLOGY, 1982, 31 (06) : 1089 - 1095
  • [3] BALZARINI J, 1982, 4TH P INT ROUND TABL, P275
  • [4] 5-IODOACETAMIDOMETHYL-2'-DEOXYURIDINE 5'-PHOSPHATE - SELECTIVE INHIBITOR OF MAMMALIAN THYMIDYLATE SYNTHETASES
    BARFKNECHT, RL
    HUETROSE, RA
    KAMPF, A
    MERTES, MP
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (16) : 5041 - 5043
  • [5] SYNTHESIS OF NUCLEOSIDES DERIVED FROM 5-ETHYNYLURACIL AND 5-ETHYNYL-CYTOSINE
    BARR, PJ
    JONES, AS
    SERAFINOWSKI, P
    WALKER, RT
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1978, (10): : 1263 - 1267
  • [6] 5(ALPHA-BROMOACETYL)-2'-DEOXYURIDINE 5'-PHOSPHATE - MECHANISM BASED AFFINITY LABEL FOR THYMIDYLATE SYNTHETASE
    BROUILLETTE, CB
    CHANG, CTC
    MERTES, MP
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1979, 87 (02) : 613 - 618
  • [7] 5-CYANO-2'-DEOXYURIDINE 5'-PHOSPHATE - POTENT COMPETITIVE INHIBITOR OF THYMIDYLATE SYNTHETASE
    CHANG, CTC
    EDWARDS, MW
    TORRENCE, PF
    MERTES, MP
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (09) : 1137 - 1139
  • [8] SYNTHESIS OF 5-SELENIUM-SUBSTITUTED URACIL DERIVATIVES - INHIBITION OF THYMIDYLATE SYNTHETASE BY 5-HYDROSELENO-2'-DEOXYURIDYLATE
    CHOI, S
    KALMAN, TI
    BARDOS, TJ
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (06) : 618 - 621
  • [9] COHEN SS, 1971, ANN NY ACAD SCI, V186, P292
  • [10] THYMIDYLATE SYNTHETASE - TARGET ENZYME IN CANCER CHEMOTHERAPY
    DANENBERG, PV
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 473 (02) : 73 - 92
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