ACID-SECRETION, 1932-92 - ADVANCES, ADAPTATIONS, AND PARADOXES

被引：9

作者：

MARKS, IN ^{[1
]}

LOUW, JA ^{[1
]}

YOUNG, GO ^{[1
]}

机构：

[1] GROOTE SCHUUR HOSP, CAPE TOWN 7925, SOUTH AFRICA

来源：

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 1992年 / 27卷

关键词：

ACID REBOUND AFTER H-2 BLOCKADE; ACID SUPPRESSION AFTER OMEPRAZOLE; AGING AND ACID SECRETION; HELICOBACTER-PYLORI; NEONATAL ACID SECRETION; PARIETAL CELL ACTIVATION; PARIETAL CELL DEVELOPMENT; PARIETAL CELL MASS; PHYSIOLOGICAL ROLE OF ACID SECRETION; TOLERANCE TO H-2-RECEPTOR ANTAGONISTS;

D O I：

10.3109/00365529209095999

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

This paper reviews the evolution of our understanding of various aspects of gastric acid secretion over the past 60 years. Embryologic aspects and neonatal acid secretion are considered, and the relationship between parietal cell mass and acid secretion and the changing concepts of parietal cell activation are discussed. The effect of aging on acid secretion and the relevance of acid secretion in health and disease are reviewed. and current views on adaptation to therapeutic inhibition of acid secretion presented. The aetiologic link between acid secretion and ulcer disease is re-examined, and the role of pepsin, growth factors, and Helicobacter pylori briefly considered.

引用

页码：7 / 13

页数：7

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