FREE-RADICAL METHODOLOGY FOR CARBOHYDRATE TO CARBOCYCLE TRANSFORMATIONS - AN EFFICIENT SYNTHESIS OF THE TRICYCLIC DIHYDROFURAN PORTION OF AZADIRACHTIN

被引：45

作者：

HENRY, KJ ^{[1
]}

FRASERREID, B ^{[1
]}

机构：

[1] DUKE UNIV,PAUL M GROSS CHEM LAB,DURHAM,NC 27708

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 18期

关键词：

D O I：

10.1021/jo00097a007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Iodo lactone 6b, derived from D-galactal, undergoes tin hydride mediated transannular radical cyclization to give the tricyclic lactone 7, which is easily converted into an advanced precursor of the tricyclic dihydrofuran portion of the potent insect antifeedant azadirachtin (1).

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页码：5128 / 5129

页数：2

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