CELL-POPULATIONS ASSOCIATED WITH ACTIVE PROBING ATTACHMENT LOSS

被引:30
作者
ZAPPA, U [1 ]
REINKINGZAPPA, M [1 ]
GRAF, H [1 ]
CASE, D [1 ]
机构
[1] WAKE FOREST UNIV,BOWMAN GRAY SCH MED,WINSTON SALEM,NC 27103
关键词
PERIODONTITIS DIAGNOSIS; FIBROBLASTS; CELLS;
D O I
10.1902/jop.1992.63.9.748
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
THE PURPOSE OF THIS STUDY was to evaluate the ability of cell populations to differentiate between untreated progressing periodontitis sites (P) and untreated non-progressing sites (NP). Pairs of biopsies were obtained from untreated periodontal patients, one biopsy from a site which had lost probing attachment of 2 mm or more within the previous month, the other biopsy from a non-progressing site. Cell populations were identified on 1 mum sections in a defined connective tissue area at the junctional epithelium. The cell types counted were fibroblasts, mast cells, monocytes/macrophages, polymorphonuclear leukocytes (PMNs), lymphoid cells, plasma cells, endothelial cells, total inflammatory cells, and the total number of cells. The number of fibroblasts, mast cells, monocytes/macrophages, and inflammatory cells, as well as their percentage of the total number of cells, differed significantly between P- and NP-sites. In addition, the actual total counts differed between groups. The difference between groups was more significant for percent fibroblasts than for any other cell type. It appears that cell populations, particularly fibroblast counts, can aid in the histological discrimination between P and NP periodontitis lesions.
引用
收藏
页码:748 / 752
页数:5
相关论文
共 37 条
[1]   INTERPROXIMAL AND BUCCAL CELL-POPULATIONS APICAL TO THE SULCUS BEFORE AND DURING EXPERIMENTAL PERIODONTITIS IN SQUIRREL-MONKEYS [J].
ADAMS, RA ;
ZANDER, HA ;
POLSON, AM .
JOURNAL OF PERIODONTOLOGY, 1981, 52 (08) :416-419
[2]  
ADAMS RA, 1979, J PERIODONTOL, V50, P7
[4]   HISTOMETRIC COMPARISON OF ACTIVE AND INACTIVE LESIONS OF ADVANCED PERIODONTITIS [J].
DAVENPORT, RH ;
SIMPSON, DM ;
HASSELL, TM .
JOURNAL OF PERIODONTOLOGY, 1982, 53 (05) :285-295
[5]   NEUTROPHIL-MEDIATED DAMAGE TO HUMAN PERIODONTAL LIGAMENT-DERIVED FIBROBLASTS - ROLE OF LIPOPOLYSACCHARIDE [J].
DEGUCHI, S ;
HORI, T ;
CREAMER, H ;
GABLER, W .
JOURNAL OF PERIODONTAL RESEARCH, 1990, 25 (05) :293-299
[6]  
ELIAS JA, 1989, J IMMUNOL, V142, P509
[7]  
FULLNER H, 1969, J DENT RES, V48, P63
[9]   PATTERNS OF PROGRESSION AND REGRESSION OF ADVANCED DESTRUCTIVE PERIODONTAL-DISEASE [J].
GOODSON, JM ;
TANNER, ACR ;
HAFFAJEE, AD ;
SORNBERGER, GC ;
SOCRANSKY, SS .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1982, 9 (06) :472-481
[10]   PROGRESSION OF UNTREATED PERIODONTITIS AS ASSESSED BY SUBTRACTION RADIOGRAPHY [J].
HAUSMANN, E ;
DUNFORD, R ;
WIKESJO, U ;
CHRISTERSSON, L ;
MCHENRY, K .
JOURNAL OF PERIODONTAL RESEARCH, 1986, 21 (06) :716-721