A convergent synthesis of a novel non-peptidyl growth hormone secretagogue, L-692,429

被引：11

作者：

Bhupathy, M

Bergan, JJ

McNamara, JM

Volante, RP

Reider, PJ

机构：

[1] Department of Process Research, Merck Research Laboratories R80Y-240, Rahway, NJ 07065-0900

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 52期

关键词：

D O I：

10.1016/0040-4039(95)02033-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical, convergent synthesis of L-692,429 (1) from three key intermediates - the 3-aminobenzlactam 2, the beta-lactam 3 and the biphenyltetrazole 4 is described. The mechanism of the coupling reaction in which 3 is used as a beta-aminoacid equivalent is also presented.

引用

收藏

页码：9445 / 9448

页数：4

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