FACIAL DIASTEREOSELECTIVITY IN THE PATERNO-BUCHI REACTION OF CHIRAL SILYL ENOL ETHERS

被引：26

作者：

Bach, T ^{[1
]}

Jodicke, K ^{[1
]}

Kather, K ^{[1
]}

Hecht, J ^{[1
]}

机构：

[1] UNIV MUNSTER, INST ORGAN CHEM, D-48149 MUNSTER, GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1995年 / 34卷 / 20期

关键词：

ASYMMETRIC SYNTHESES; CYCLOADDITIONS; OXETANES; PATERNO-BUCHI REACTIONS; PHOTOCHEMISTRY;

D O I：

10.1002/anie.199522711

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A single element of chirality determines the configuration of the three newly formed stereogenic centers in the title reaction [Eq. (a)]. In particular, large (R = SiMe2Ph,tBu) and polar (R = OMe) substituents induce good diastereoselectivities. Simple ring‐opening reactions facilitate a stereoselective approach to acyclic products. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：2271 / 2273

页数：3

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