VISUALIZATION OF HYPOXIA-INDUCED GLUTAMATE RELEASE IN GERBIL HIPPOCAMPAL SLICE

被引：34

作者：

MITANI, A

KADOYA, F

NAKAMURA, Y

KATAOKA, K

机构：

[1] Department of Physiology, School of Medicine, Ehime University, Ehime

来源：

NEUROSCIENCE LETTERS | 1991年 / 122卷 / 02期

关键词：

MICROFLUOROMETRY; GLUTAMATE; NADH; HYPOXIA; HIPPOCAMPUS;

D O I：

10.1016/0304-3940(91)90849-O

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Microfluorometry was used to investigate distribution of hypoxia-induced release of glutamate. Mongolian gerbil hippocampal slice was perfused in a medium containing glutamate dehydrogenase and NAD+. Release of glutamate into extracellular space caused an increase in fluorescence due to the formation of NADH. The hypoxia-induced release of glutamate was gradually increased throughout the slice: no significant difference was detected among CA1 region, CA3 region and the dentate gyrus.

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页码：167 / 170

页数：4

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