ALLOIMMUNE THROMBOCYTOPENIA - INUTERO TREATMENT BY HIGH-DOSES OF INTRAVENOUS GAMMA-GLOBULINS

被引：4

作者：

POULAIN, P

KAPLAN, C

LEBERRE, C

MILON, J

BERGERON, C

GRALL, JY

机构：

[1] Institut National de Transfusion Sanguine, Paris

[2] Department of Obstetrics, Hôpital Sud, Paris

[3] Centre Régional de Transfusion Sanguine, Paris

[4] Department of Ultrasound, Paris

[5] Department of Pediatrics, Rennes

来源：

FETAL DIAGNOSIS AND THERAPY | 1992年 / 7卷 / 02期

关键词：

ALLOIMMUNE THROMBOCYTOPENIA; PLATELET ANTIGEN INCOMPATIBILITY; ANTENATAL DIAGNOSIS; PERIUMBILICAL BLOOD SAMPLING; INUTERO TREATMENT;

D O I：

10.1159/000263662

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The authors report successful in utero treatment by high doses of intravenous gamma globulins in a case of neonatal alloimmune thrombocytopenia. Early diagnosis allows an appropriate management: fetal blood sampling as early as 20 weeks of gestation; in case of fetal thrombocytopenia, treatment by intravenous gamma globulin (1.0 g/kg/b.w.) each week during 8 weeks or more; ultrasound screening of in utero hemorrhage, particularly intracranial hemorrhage; fetal blood sampling before delivery at term and in utero transfusion of platelet antigen negative in case of persistence of fetal thrombocytopenia.

引用

页码：144 / 146

页数：3

共 15 条

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[4]

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