QUANTIFICATION OF THE INVITRO ACTIVITY OF SOME COMPOUNDS WITH SPERMICIDAL ACTIVITY

被引：17

作者：

CHANTLER, E

FISHER, H

SOLANKI, S

ELSTEIN, M

机构：

[1] Department of Obstetrics and Gynaecology, University Hospital of South Manchester

来源：

CONTRACEPTION | 1992年 / 46卷 / 06期

关键词：

D O I：

10.1016/0010-7824(92)90117-C

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The in vitro spermicidal activity of the commonly used surfactant spermicides and the antiseptic chlorhexidine, were quantified in a statistically reproducible manner, using donor semen and image capture analysis. The spermicidal activity was expressed as the ED50 under defined assay conditions. Using these parameters, the order of spermicidal activity was: Menfegol > nonoxynol-9 almost-equal-to benzalkonium chloride > sodium docusate > chlorhexidine. These differences were statistically significant.

引用

页码：527 / 536

页数：10

共 21 条

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