DEAFFERENTATION SYNDROME IN THE RAT - EFFECTS OF SEX, AGE, AND LESION TYPE

被引：7

作者：

ROSSITCH, E

LYERLY, MA

OVELMENLEVITT, J

YOUNG, JN

NASHOLD, BS

机构：

[1] Division of Neurosurgery, Duke University Medical Center, Durham, NC

来源：

SURGICAL NEUROLOGY | 1992年 / 37卷 / 02期

关键词：

DEAFFERENTATION SYNDROME; ANIMAL MODEL; AUTOTOMY; AVULSION; GANGLIONECTOMY; RHIZOTOMY; SELF-MUTILATION;

D O I：

10.1016/0090-3019(92)90182-M

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A deafferentation syndrome can be produced in Sprague-Dawley rats following dorsal root sections. The behavior may be objective evidence of dysesthesias, thus serving as an experimental model to study chronic dysesthesias caused by deafferentation in humans. This article examines the effects of sex, age, and lesion type on the expression of the deafferentation syndrome in Sprague-Dawley rats. No significant differences were found in the expression of the deafferentation syndrome with respect to age and weight in male rats within the ranges studied. Sex and lesion type did alter the expression of the syndrome.

引用

页码：89 / 93

页数：5

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