DEBRISOQUINE POLYMORPHISM AND THE METABOLISM AND ACTION OF METOPROLOL, TIMOLOL, PROPRANOLOL AND ATENOLOL

被引：69

作者：

LENNARD, MS ^{[1
]}

TUCKER, GT ^{[1
]}

SILAS, JH ^{[1
]}

WOODS, HF ^{[1
]}

机构：

[1] CLATTERBRIDGE HOSP,HYPERTENS UNIT,WIRRAL L63 2JY,MERSEYSIDE,ENGLAND

来源：

关键词：

D O I：

10.3109/00498258609050250

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：435 / 447

页数：13

共 43 条

[1] ALVAN G, 1982, LANCET, V1, P333
[2] BAI SA, 1983, J PHARMACOL EXP THER, V224, P62
[3] BAI TR, 1982, J ROY COLL PHYS LOND, V16, P239
[4] BALANT L, 1976, SCHWEIZ MED WOCHENSC, V106, P1043
[5] TIMOLOL PHARMACOKINETICS AND EFFECTS ON HEART-RATE AND BLOOD-PRESSURE AFTER ACUTE AND CHRONIC ADMINISTRATION
BOBIK, A
JENNINGS, GL
ASHLEY, P
KORNER, PI
[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 16 (04) : 243 - 249
[6] BOOBIS AR, 1983, MOL PHARMACOL, V23, P474
[7] GENETIC-POLYMORPHISM IN DRUG OXIDATION - INVITRO STUDIES OF HUMAN DEBRISOQUINE 4-HYDROXYLASE AND BUFURALOL 1'-HYDROXYLASE ACTIVITIES
BOOBIS, AR
MURRAY, S
HAMPDEN, CE
DAVIES, DS
[J]. BIOCHEMICAL PHARMACOLOGY, 1985, 34 (01) : 65 - 71
[8] BORG KO, 1975, ACTA PHARMACOL TOX, V36, P125
[9] CLEAVELAND CR, 1972, CLIN PHARMACOL THER, V13, P181
[10] PLASMA PROPRANOLOL LEVELS IN QUANTITATIVE ASSESSMENT OF BETA-ADRENERGIC BLOCKADE IN MAN
COLTART, DJ
SHAND, DG
[J]. BRITISH MEDICAL JOURNAL, 1970, 3 (5725) : 731 - &