PLASMINOGEN-ACTIVATOR INHIBITOR IN ACUTE STROKE

被引：6

作者：

BROCKMANN, MJ

SCHWENDEMANN, G

STIEF, TW

机构：

[1] UNIV ESSEN GESAMTHSCH,DEPT NEUROL,HUFELANDSTR 55,W-4300 ESSEN 1,GERMANY

[2] BEHRINGWERKE AG,RES LABS,W-3550 MARBURG,GERMANY

来源：

MOLECULAR AND CHEMICAL NEUROPATHOLOGY | 1991年 / 14卷 / 02期

关键词：

PLASMINOGEN ACTIVATOR INHIBITOR; STROKE; FIBRINOLYSIS; TRIGLYCERIDES;

D O I：

10.1007/BF03159933

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Plasminogen activator inhibitor activity was determined in patients (26 men, 6 women) with acute ischemic stroke (n = 28) and transient ischemic attack (TIA) (n = 4). Age-matched patients (22 men, 10 women) with various nonvascular neurologic diseases served as controls. Plasma levels of plasminogen activator inhibitor activity were significantly higher in the stroke group (p < 0.003). Serum triglycerides and plasminogen activator inhibitor activity correlated positively in the stroke group (p < 0.03) and in controls (p < 0.0001). Our data suggest a possible involvement of plasminogen activator inhibitor activity in the pathophysiology of stroke.

引用

页码：143 / 150

页数：8

共 34 条

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