THE FINITE POLYGENIC MIXED-MODEL - AN ALTERNATIVE FORMULATION FOR THE MIXED-MODEL OF INHERITANCE

被引：57

作者：

FERNANDO, RL

STRICKER, C

ELSTON, RC

机构：

[1] LOUISIANA STATE UNIV,MED CTR,DEPT BIOMETRY & GENET,NEW ORLEANS,LA 70112

[2] LOUISIANA STATE UNIV,MED CTR,CTR MOLEC & HUMAN GENET,NEW ORLEANS,LA 70112

来源：

THEORETICAL AND APPLIED GENETICS | 1994年 / 88卷 / 05期

关键词：

MIXED MODEL INHERITANCE; LIKELIHOOD;

D O I：

10.1007/BF01240920

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

This paper presents a mixed model of inheritance with a finite number of polygenic loci. This model leads to a likelihood that can be calculated using efficient algorithms developed for oligogenic models. For comparison, likelihood profiles were obtained for the finite polygenic mixed model, the usual mixed model with exact and approximate calculations, and for a class D regressive model. The profiles for the finite polygenic mixed model were closest to the profiles for the usual mixed model with exact calculations.

引用

页码：573 / 580

页数：8

共 26 条

[1] ON THE STATISTICAL DETERMINATION OF MAJOR GENE MECHANISMS IN CONTINUOUS HUMAN TRAITS - REGRESSIVE MODELS [J].