ASYMMETRIC ALLYLIC AMINATION CATALYZED BY CHIRAL FERROCENYLPHOSPHINE-PALLADIUM COMPLEXES

被引：117

作者：

HAYASHI, T

KISHI, K

YAMAMOTO, A

ITO, Y

机构：

[1] HOKKAIDO UNIV,GRAD SCH PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN

[2] KYOTO UNIV,DEPT SYNTHET CHEM,KYOTO 606,JAPAN

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(00)88870-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium complex bearing chiral (hydroxyalkyl)ferrocenylphosphine ligand was found to be a highly regio-and stereoselective catalyst for the asymmetric allylic amination of 2-butenyl acetates with benzylamine, the nucleophilic attack of the amine taking place selectively on the more substituted end of the π-allylpalladium intermediate to give optically active 3-benzyamino- 1-butene of up to 84% ee. © 1990.

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页码：1743 / 1746

页数：4

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