DISPIROKETALS IN SYNTHESIS .8. REGIOSELECTIVE PROTECTION OF D-GLUCOPYRANOSE SUBSTRATES

被引：19

作者：

ENTWISTLE, DA ^{[1
]}

HUGHES, AB ^{[1
]}

LEY, SV ^{[1
]}

VISENTIN, G ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,DEPT CHEM,CAMBRIDGE CB2 1EW,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)75815-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new process for the efficient regioselective formation of 1,8,13,16-tetraoxadispiro[5.0.5.4]hexadecanes (dispiroketals) of various D-elucopyranosyl substrates by the chiral recognition of enantiomeric trans 1,2-diol relationships is described. This was achieved using the novel enantiomerically pure 2,2'-disubstituted 3,3',4,4'-tetrahydro-6,6'-bi-2H-pyrans 1, 2 and 11. New conditions for the removal of dispiroketal protecting groups are presented.

引用

页码：777 / 780

页数：4

共 6 条

[1] SELECTIVE ESTERIFICATION OF METHYL ALPHA-D-GLUCOPYRANOSIDE [J].