HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ASSAY OF IOMEPROL IN PLASMA AND URINE

被引：9

作者：

LORUSSO, V

POGGESI, I

DALFIUME, D

TIRONE, P

机构：

[1] Bracco Research Department, 20134 Milan

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1990年 / 525卷 / 02期

关键词：

D O I：

10.1016/S0378-4347(00)83416-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A high-performance liquid chromatographic method for assaying the radiographic contrast agent iomeprol in plasma and urine samples is described. Before reversed-phase chromatography, the biological fluids are treated with ion-exchange resins and iopamidol is added as internal standard. The compounds are monitored during elution by ultraviolet-visible spectrometry at 245 nm. The method shows good precision and accuracy and gives similar results to X-ray fluorescence analysis. © 1990.

引用

页码：401 / 409

页数：9

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