学术探索
学术期刊
新闻热点
数据分析
智能评审

REACTION OF SERINE PROTEASES WITH SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS AND 3-ALKOXY-7-AMINO-4-CHLOROISOCOUMARINS - NEW REACTIVE MECHANISM-BASED INHIBITORS

被引：92
作者：
HARPER, JW [1 ]
POWERS, JC [1 ]
机构：
[1] GEORGIA INST TECHNOL,SCH CHEM,ATLANTA,GA 30332
来源：
BIOCHEMISTRY | 1985年 / 24卷 / 25期
关键词：
D O I：
10.1021/bi00346a028
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：7200 / 7213
页数：14
相关论文
共 46 条
  • [1] INACTIVATION OF ALPHA-CHYMOTRYPSIN BY A BIFUNCTIONAL REAGENT, 2-BROMOMETHYL-3,I-BENZOXAZIN-4-ONE
    ALAZARD, R
    BECHET, JJ
    DUPAIX, A
    YON, J
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 309 (02) : 379 - 396
  • [2] ASHE BM, 1981, J BIOL CHEM, V256, P1603
  • [3] BARRETT AJ, 1981, METHOD ENZYMOL, V80, P581
  • [4] INACTIVATION OF ALPHA-CHYMOTRYPSIN BY NEW BIFUNCTIONAL REAGENTS - HALOMETHYLATED DERIVATIVES OF DIHYDROCOUMARINS
    BECHET, JJ
    DUPAIX, A
    BLAGOEVA, I
    [J]. BIOCHIMIE, 1977, 59 (03) : 231 - 239
  • [5] INACTIVATION OF ALPHA-CHYMOTRYPSIN BY A BIFUNCTIONAL REAGENT, 3,4-DIHYDRO-3,4-DIBROMO-6-BROMOMETHYLCOUMARIN
    BECHET, JJ
    DUPAIX, A
    YON, J
    WAKSELMA.M
    ROBERT, JC
    VILKAS, M
    [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 35 (03): : 527 - 539
  • [6] DETERMINATION OF CONCENTRATION OF HYDROLYTIC ENZYME SOLUTIONS - ALPHA-CHYMOTRYPSIN TRYPSIN PAPAIN ELASTASE SUBTILISIN AND ACETYLCHOLINESTERASE
    BENDER, ML
    BEGUECAN.ML
    BLAKELEY, RL
    BRUBACHER, LJ
    FEDER, J
    GUNTER, CR
    KEZDY, FJ
    KILLHEFFER, JV
    MARSHALL, TH
    MILLER, CG
    ROESKE, RW
    STOOPS, JK
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (24) : 5890 - +
  • [7] SYNTHESIS AND ANALYTICAL USE OF A HIGHLY SENSITIVE AND CONVENIENT SUBSTRATE OF ELASTASE
    BIETH, J
    SPIESS, B
    WERMUTH, CG
    [J]. BIOCHEMICAL MEDICINE, 1974, 11 (04): : 350 - 357
  • [8] A NOVEL CONNECTOR LINKAGE APPLICABLE IN PRODRUG DESIGN
    CARL, PL
    CHAKRAVARTY, PK
    KATZENELLENBOGEN, JA
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (05) : 479 - 480
  • [9] SENSITIVE SUBSTRATES FOR HUMAN-LEUKOCYTE AND PORCINE PANCREATIC ELASTASE - STUDY OF THE MERITS OF VARIOUS CHROMOPHORIC AND FLUOROGENIC LEAVING GROUPS IN ASSAYS FOR SERINE PROTEASES
    CASTILLO, MJ
    NAKAJIMA, K
    ZIMMERMAN, M
    POWERS, JC
    [J]. ANALYTICAL BIOCHEMISTRY, 1979, 99 (01) : 53 - 64
  • [10] ACTIVE-SITE MAPPING OF BOVINE AND HUMAN-BLOOD COAGULATION SERINE PROTEASES USING SYNTHETIC PEPTIDE 4-NITROANILIDE AND THIO ESTER SUBSTRATES
    CHO, K
    TANAKA, T
    COOK, RR
    KISIEL, W
    FUJIKAWA, K
    KURACHI, K
    POWERS, JC
    [J]. BIOCHEMISTRY, 1984, 23 (04) : 644 - 650
12345