DIASTEREOMERIC 6-DESOXY-6-SPIRO-ALPHA-METHYLENE-GAMMA-BUTYROLACTONE DERIVATIVES OF NALTREXONE AND OXYMORPHONE - SELECTIVE IRREVERSIBLE INHIBITION OF NALTREXONE BINDING IN AN OPIOID RECEPTOR PREPARATION BY A CONFORMATIONALLY RESTRICTED MICHAEL ACCEPTOR LIGAND

被引:15
作者
KOOLPE, GA
NELSON, WL
GIOANNINI, TL
ANGEL, L
SIMON, EJ
机构
[1] UNIV WASHINGTON,SCH PHARM,DEPT MED CHEM,SEATTLE,WA 98195
[2] NYU MED CTR,DEPT PSYCHIAT & PHARMACOL,NEW YORK,NY 10016
关键词
D O I
10.1021/jm00378a032
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:1718 / 1723
页数:6
相关论文
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