DIFFERENTIATION BETWEEN MOUSE-VIRULENT AND MOUSE-AVIRULENT STRAINS OF TOXOPLASMA-GONDII BY A MONOCLONAL-ANTIBODY RECOGNIZING A 27-KILODALTON ANTIGEN

被引：24

作者：

BOHNE, W ^{[1
]}

GROSS, U ^{[1
]}

HEESEMANN, J ^{[1
]}

机构：

[1] UNIV WURZBURG,INST HYG & MICROBIOL,JOSEF SCHNEIDER STR 2,W-8700 WURZBURG,GERMANY

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1993年 / 31卷 / 06期

关键词：

D O I：

10.1128/JCM.31.6.1641-1643.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Using a murine monoclonal antibody, we were able to differentiate between mouse-virulent and -avirulent strains of Toxoplasma gondii. Monoclonal antibody TB6G5 was reactive with eight clinical mouse-avirulent isolates but not with mouse-virulent laboratory strains RH and BK. The antibody-reactive antigen was identified by indirect immunofluorescence and immunoblot as a 27-kDa cytoplasmic protein expressed by tachyzoites as well as by bradyzoites.

引用

页码：1641 / 1643

页数：3

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