ASSOCIATION OF SERUM HEMOLYTIC COMPLEMENT LEVELS WITH MAJOR HISTOCOMPATIBILITY COMPLEX IN CHICKENS

被引：44

作者：

CHANH, TC

BENEDICT, AA

ABPLANALP, H

机构：

[1] UNIV HAWAII, DEPT MICROBIOL, HONOLULU, HI 96822 USA

[2] UNIV CALIF DAVIS, DEPT AVIAN SCI, DAVIS, CA 95616 USA

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 1976年 / 144卷 / 02期

关键词：

D O I：

10.1084/jem.144.2.555

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The total hemolytic complement (C) levels in inbred line 7 chicks and adults were lower than C levels in inbred lines 2 and 3, and in outbred chickens of the same age. In all birds, adult levels of C were obtained in 5-6 wk old chickens. Analysis of F1 and F3 generations clearly showed that the C level in chickens was determined by a dominant gene(s) associated with the major histocompatibility complex. Finding this association in a nonmammal strengthens the importance of the relationship between closely linked gross controlling histocompatibility, immune responsiveness, mixed leukocyte reaction and C activity.

引用

页码：555 / 561

页数：7

共 23 条

[1] GENETIC-CONTROL OF IMMUNE-RESPONSES IN CHICKENS .1. RESPONSES TO A TERPOLYMER OF POLY(GLU60ALA30TYR10) ASSOCIATED WITH MAJOR HISTOCOMPATIBILITY COMPLEX [J].