IMIDAZOLE - SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE

被引：359

作者：

MONCADA, S

BUNTING, S

MULLANE, K

THOROGOOD, P

VANE, JR

RAZ, A

NEEDLEMAN, P

机构：

[1] WELLCOME RES LABS,BECKENHAM BR3 3BS,KENT,ENGLAND

[2] WASHINGTON UNIV,SCH MED,DEPT PHARMACOL,ST LOUIS,MO 63110

来源：

PROSTAGLANDINS | 1977年 / 13卷 / 04期

关键词：

D O I：

10.1016/0090-6980(77)90232-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：611 / 618

页数：8

共 24 条

[1] PROSTACYCLIN (PGX) IS ENDOGENOUS METABOLITE RESPONSIBLE FOR RELAXATION OF CORONARY-ARTERIES INDUCED BY ARACHIDONIC-ACID [J].

DUSTING, GJ ;

MONCADA, S ;

VANE, JR .

PROSTAGLANDINS, 1977, 13 (01) :3-15

[2] PROSTAGLANDIN ANTAGONISM BY SODIUM PARA-BENZYL-4-[1-OXO-2-(4-CHLOROBENZYL)-3-PHENYLPROPYL]PHENYLPHOSPHONATE (N-0164) [J].

EAKINS, KE ;

RAJADHYAKSHA, V ;

SCHROER, R .

BRITISH JOURNAL OF PHARMACOLOGY, 1976, 58 (03) :333-339

[3]

FURGHGOTT RF, 1955, PHARMAC REV, V7, P183

[4] RELEASE OF PROSTAGLANDINS AND RABBIT AORTA CONTRACTING SUBSTANCE (RCS) FROM RABBIT SPLEEN AND ITS ANTAGONISM BY ANTIINFLAMMATORY DRUGS [J].

GRYGLEWSKI, R ;

VANE, JR .

BRITISH JOURNAL OF PHARMACOLOGY, 1972, 45 (01) :37-+

[5] ARTERIAL-WALLS ARE PROTECTED AGAINST DEPOSITION OF PLATELET THROMBI BY A SUBSTANCE (PROSTAGLANDIN-X) WHICH THEY MAKE FROM PROSTAGLANDIN ENDOPEROXIDES [J].

GRYGLEWSKI, RJ ;

BUNTING, S ;

MONCADA, S ;

FLOWER, RJ ;

VANE, JR .

PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1976, 12 (05) :685-713

[6] PROSTAGLANDIN ENDOPEROXIDES .4. EFFECTS ON SMOOTH-MUSCLE [J].

HAMBERG, M ;

HEDQVIST, P ;

STRANDBERG, K ;

SVENSSON, J ;

SAMUELSSON, B .

LIFE SCIENCES, 1975, 16 (03) :451-462

[7] ISOLATION AND STRUCTURE OF 2 PROSTAGLANDIN ENDOPEROXIDES THAT CAUSE PLATELET-AGGREGATION [J].

HAMBERG, M ;

SVENSSON, J ;

WAKABAYASHI, T ;

SAMUELSSON, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (02) :345-349

[8] THROMBOXANES - NEW GROUP OF BIOLOGICALLY-ACTIVE COMPOUNDS DERIVED FROM PROSTAGLANDIN ENDOPEROXIDES [J].

HAMBERG, M ;

SVENSSON, J ;

SAMUELSSON, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (08) :2994-2998

[9] POLYMORPHONUCLEAR LEUKOCYTES PRODUCE THROMBOXANE-A-2-LIKE ACTIVITY DURING PHAGOCYTOSIS [J].

HIGGS, GA ;

BUNTING, S ;

MONCADA, S ;

VANE, JR .

PROSTAGLANDINS, 1976, 12 (05) :749-757

[10]

ISAKSON PC, IN PRESS

← 1 2 3 →