APPLICABILITY OF PASCAL DISTRIBUTION TO QUANTAL ANALYSIS FOR NONSTATIONARY RELEASE OF NEUROTRANSMITTER

被引:11
作者
HIGASHIMA, M
SAWADA, S
YAMAMOTO, C
机构
[1] Department of Physiology, Faculty of Medicine, Kanazawa University, Kanazawa
关键词
Binomial distribution; Non-stationarity; Pascal distribution; Poisson distribution; Quantal analysis; Transmitter release;
D O I
10.1016/0304-3940(90)90460-Q
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
In order to assess the applicability of theoretical distributions to statistical analysis of neurotransmitter release, we made mathematical approaches such as derivation of frequency-generating function of the distributions, and obtained a result that a frequency distribution of the number of quanta released by the consecutive stimulations is described by a Pascal distribution when the Poisson parameter m varies temporally according to a gamma (γ) distribution. Therefore, if the experimentally obtained distribution fits with a Pascal distribution, this suggests the non-stationary nature of the release mechanism. © 1990.
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页码:231 / 236
页数:6
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