SYMPATHETIC DENERVATION OF THE IRIS DILATOR IN NONINSULIN-DEPENDENT DIABETES

被引:11
作者
FULK, GW
BOWER, A
MCBRIDE, K
BOATRIGHT, R
机构
[1] College of Optometry, Northeastern State University, Tahlequah, OK
关键词
NONINSULIN-DEPENDENT DIABETES-MELLITUS; SYMPATHETIC NEUROPATHY; PUPIL DILATION; BLOOD GLUCOSE;
D O I
10.1097/00006324-199112000-00008
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Twenty-three subjects with noninsulin-dependent diabetes mellitus (NIDDM) and 23 age- and sex-matched controls were tested for sympathetic denervation of the iris dilator by comparing the mydriatic effect of the combination of 1% phenylephrine and 1% tropicamide with that of 1% tropicamide alone. Most of the diabetic subjects had no clinical signs of severe diabetic complications. Nine diabetics and two controls showed sympathetic denervation, defined as a 1 mm or greater dilation due the addition of 1% phenylephrine. One of those two controls had a recent history of vascular headache. The diabetics with pupillary neuropathy had higher glycosylated hemoglobin percentages and a history of higher fasting blood sugars (FBS's) than the diabetics with normal pupils. Our results show that pupillary neuropathy can develop in persons with diabetes, often before the other complications of diabetes become manifest.
引用
收藏
页码:954 / 956
页数:3
相关论文
共 10 条
[1]  
Smith S.E., Smith S.A., Brown P.M., Fox C., Sonksen P.H., Pupillary signs in diabetic autonomic neuropathy, Br Med J, 2, pp. 924-927, (1978)
[2]  
Hreidarsson A.B., Pupil size in insulin-dependent diabetes relationship to duration, metabolic control, and long-term manifestations, Diabetes, 31, pp. 442-448, (1982)
[3]  
Smith S.A., Smith S.E., Evidence for a neuropathic etiology in the small pupil of diabetes mellitus, Br J Ophthalmol, 67, pp. 89-93, (1983)
[4]  
Harris M.I., Classification and diagnostic criteria for diabetes and other categories of glucose intolerance, United States Department of Health and Human Services, (1985)
[5]  
Sievers M.L., Fisher J.R., Diabetes in North American Indians, United States Department of Health and Human Services, (1985)
[6]  
Pfeifer M.A., Cook D., Brodsky J., Tice D., Parrish D., Reenan A, Halter JB, Porte D. Cuantitative evaluation of sympathetic and parasympathetic control of iris function, Diabetes Care, 5, pp. 518-528, (1982)
[7]  
Bartlett J.D., Jaanus S.D., Clinical Ocular Pharmacology, (1984)
[8]  
Kunkle E.C., Erson W.B., Significance of minor eye signs in headache of migraine type, Arch Ophthalmol, 65, pp. 504-507, (1961)
[9]  
Grimson B.S., Thompson H.S., Raeder’s syndrome: A clinical review, Surv Ophthalmol, 24, pp. 199-204, (1980)
[10]  
Grimson B.S., Thompson H.S., Horner’s syndrome: Overall view of 120 cases, Topics in Neuro-Ophthalology, pp. 151-156, (1979)