Serum insulin-like growth factor-I (IGF-I) in normal Japanese adults

被引：11

作者：

Kitano, M ^{[1
]}

Shimizu, T ^{[1
]}

Yamazaki, Y ^{[1
]}

Umezu, Y ^{[1
]}

Arakawa, Y ^{[1
]}

Daimon, Y ^{[1
]}

机构：

[1] TORANOMON GEN HOSP,CLIN ENDOCRINE LAB,MINATO KU,TOKYO 105,JAPAN

来源：

ENDOCRINE JOURNAL | 1995年 / 42卷 / 06期

关键词：

IGF-I; reference values for Japanese adults;

D O I：

10.1507/endocrj.42.767

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To evaluate surgical and medical treatment of GH-producing pituitary tumors and GH supplement to GH-deficient patients, we determined the reference values for serum IGF-I in Japanese adults. The serum IGF-I concentration in 454 apparently healthy subjects (246 men aged 21-70 years and 208 women aged 21-72 years) was measured with a commercial RIA kit after acid-ethanol extraction. The concentration of serum IGF-I decreased with age in both sexes. The IGF-I in females was significantly higher than that in males in the group aged 21-30 years and lower in the group aged 61-72 years. We conclude that an age- or sex-related standard is necessary for comparing IGF-I values in patients.

引用

页码：767 / 770

页数：4

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