END-TIDAL CO2 PRESSURE IN THE MONITORING OF CARDIAC-OUTPUT DURING CANINE HEMORRHAGIC-SHOCK

被引:13
作者
DUBIN, A
SILVA, C
CALVO, G
VALLI, J
FARINA, O
ESTENSSORO, E
MORDUJOVICH, P
机构
[1] Catedra de Farmacologia, Facultad de Ciencias Medicas, Universidad Nacional de La Plata, La Plata, Buenos Aires
关键词
D O I
10.1016/0883-9441(90)90008-W
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The value of end-Tidal CO2 pressure (PETCO2) in monitoring circulatory status has been recently established in cardiac arrest. In an effort to extend its usefulness to other low-flow states, we studied the changes of PETCO2 during progressive hemorrhage in anesthetized, mechanically ventilated dogs. PETCO2 correlated with cardiac index (CI) in a logarithmic way (r = .95, P < .001), not only in the whole group but in any individual experiment as well. Venoarterial and arterial-end-tidal CO2 gradients also correlated with CI (r = .85, P < .001 and r = .63, P < .001, respectively). These results suggest that cardiac output reductions are followed by increments in respiratory dead space, so CO2 accumulates in venous blood and its pulmonary excretion is decreased. In this way, sequential changes in PETCO2 during mechanical ventilation could noninvasively contribute to hemodynamic evaluation in hemorrhagic shock. © 1990.
引用
收藏
页码:42 / 46
页数:5
相关论文
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