HIGH-LEVEL EXPRESSION OF THE FTSA PROTEIN INHIBITS CELL SEPTATION IN ESCHERICHIA-COLI K-12

被引:34
作者
WANG, HC
GAYDA, RC
机构
[1] LOUISIANA STATE UNIV,DEPT MICROBIOL,BATON ROUGE,LA 70803
[2] LOUISIANA STATE UNIV,LOUISIANA AGR EXPT STN,BATON ROUGE,LA 70803
关键词
D O I
10.1128/jb.172.8.4736-4740.1990
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
DNA fragments encoding the ftsA gene were subcloned into plasmids downstream of a lac promoter or a tac promoter. These plasmid constructs, when transformed into wild-type and mutant strains, inhibited normal cell septation, causing the formation of long nonseptate filaments. This phenotype is due to overproduction of the FtsA protein.
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页码:4736 / 4740
页数:5
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