ENANTIOSPECIFIC SYNTHESIS OF THE TRICYCLIC NUCLEUS OF ACETOXYCRENULIDE BY CLAISEN RING EXPANSION

被引:24
作者
EZQUERRA, J [1 ]
WEI, H [1 ]
PAQUETTE, LA [1 ]
机构
[1] OHIO STATE UNIV,EVANS CHEM LABS,COLUMBUS,OH 43210
关键词
D O I
10.1016/S0040-4039(00)97221-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The known R lactone 4 has been transformed in 9 steps into optically pure 2, a molecule possessing the ring system characteristic of the crenulide diterpenes. In the key step, chirality transfer is accomplished via a Z-selective Claisen ring expansion. © 1990.
引用
收藏
页码:6979 / 6982
页数:4
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