GLUTAMATE-DEHYDROGENASE IS NOT ESSENTIAL FOR GLUTAMATE FORMATION BY CORYNEBACTERIUM-GLUTAMICUM

被引：30

作者：

BORMANNELKHOLY, ER ^{[1
]}

EIKMANNS, BJ ^{[1
]}

GUTMANN, M ^{[1
]}

SAHM, H ^{[1
]}

机构：

[1] FORSCHUNGSZENTRUM JULICH, FORSCHUNGSZENTRUM, INST BIOTECHNOL 1, POSTFACH 1913, W-5170 JULICH 1, GERMANY

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 1993年 / 59卷 / 07期

关键词：

D O I：

10.1128/AEM.59.7.2329-2331.1993

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Two Corynebacterium glutamicum strains, one being glutamate dehydrogenase (GDH) negative and the other possessing 11-fold-higher specific GDH activity than the parental wild type, were constructed and used to analyze the role of GDH in C. glutamicum. The results indicate (i) that GDH is dispensable for glutamate synthesis required for growth and (ii) that although a high level of GDH increases the intracellular glutamate pool, the level of GDH has no influence on glutamate secretion.

引用

页码：2329 / 2331

页数：3

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