SMALL-CELL LUNG-CARCINOMA IN A PATIENT WITH SOTOS SYNDROME - ARE GENES AT 3P21 INVOLVED IN BOTH CONDITIONS

被引：22

作者：

COLE, TRP

HUGHES, HE

JEFFREYS, MJ

WILLIAMS, GT

ARNOLD, MM

机构：

[1] QUEEN ALEXANDRA HOSP, DEPT PATHOL, PORTSMOUTH PO6 3LY, ENGLAND

[2] UNIV WALES COLL MED, DEPT PATHOL, CARDIFF CF4 4XW, S GLAM, WALES

[3] QUEEN ALEXANDRA HOSP, DEPT MED, PORTSMOUTH PO6 3LY, ENGLAND

来源：

JOURNAL OF MEDICAL GENETICS | 1992年 / 29卷 / 05期

关键词：

D O I：

10.1136/jmg.29.5.338

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A 22 year old female with Sotos syndrome and a small cell lung carcinoma is described. This case is of interest not only because of the somatic growth pattern, atypical of Sotos syndrome, but also because of the association with a rare tumour. Of significance is the possible role of mutations at 3p21 in the aetiology of Sotos syndrome and tumour development.

引用

页码：338 / 341

页数：4

共 24 条

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