CERVICAL LYMPHATICS, THE BLOOD-BRAIN-BARRIER AND THE IMMUNOREACTIVITY OF THE BRAIN - A NEW VIEW

被引:508
作者
CSERR, HF [1 ]
KNOPF, PM [1 ]
机构
[1] BROWN UNIV, MOLEC CELL & DEV BIOL SECT, PROVIDENCE, RI 02912 USA
来源
IMMUNOLOGY TODAY | 1992年 / 13卷 / 12期
关键词
D O I
10.1016/0167-5699(92)90027-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
This new view of the immunoreactivity of the normal brain is based on three key components. First, there is an active and highly-regulated communication between the brain and the central immune organs. Secondly, the connection from the brain to the draining nodes is much larger than previously appreciated. And third, the blood-brain barrier, by virtue of its selective permeability properties, contributes to the regulation of immunoregulatory cells and molecules in the brain cell microenvironment.
引用
收藏
页码:507 / 512
页数:6
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