HUMAN PHARMACOKINETIC AND PHARMACODYNAMIC STUDIES ON ATENOLOL (ICI 66,082), A NEW CARDIOSELECTIVE BETA-ADRENOCEPTOR BLOCKING DRUG

被引：124

作者：

CONWAY, FJ

FITZ GERALD, JD

MCAINSH, J

ROWLANDS, DJ

SIMPSON, WT

机构：

[1] ICI LTD, DIV PHARM, DEPT BIOL, MACCLESFIELD SK10 4TG, CHESHIRE, ENGLAND

[2] MCMASTER UNIV, DEPT MED, HAMILTON, ONTARIO, CANADA

[3] ICI LTD, DIV PHARM, DEPT SAFETY MED, MACCLESFIELD SK10 4TG, CHESHIRE, ENGLAND

[4] MANCHESTER ROY INFIRM, DEPT CARDIOL, MANCHESTER, ENGLAND

[5] ICI LTD, DIV PHARM, DEPT CLIN RES, MACCLESFIELD SK10 4TG, CHESHIRE, ENGLAND

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1976年 / 3卷 / 02期

关键词：

D O I：

10.1111/j.1365-2125.1976.tb00602.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：267 / 272

页数：6

共 7 条

[1]

BARRETT AM, 1973, BRIT J PHARMACOL, V48, pP340

[2] BLOCKADE OF PERIPHERAL VASCULAR-RESPONSES TO ISOPRENALINE BY 3 BETA-ADRENOCEPTOR ANTAGONISTS IN ANESTHETIZED DOG [J].

HAINSWORTH, R ;

KARIM, F ;

STOKER, JB .

BRITISH JOURNAL OF PHARMACOLOGY, 1974, 51 (02) :161-168

[3]

HAINSWORTH R, 1973, BRIT J PHARMACOL, V48, P342

[4] ACTIONS OF A NEW BETA-ADRENOCEPTOR BLOCKING DRUG, ICI 66082, ON RABBIT PAPILLARY-MUSCLE AND ON DOG HEART [J].

HARRY, JD ;

KNAPP, MF ;

LINDEN, RJ .

BRITISH JOURNAL OF PHARMACOLOGY, 1974, 51 (02) :169-177

[5]

HARRY JD, 1973, BRIT J PHARMACOL, V48, pP340

[6] GAS-CHROMATOGRAPHIC DETERMINATION OF ATENOLOL IN BIOLOGICAL SAMPLES [J].

SCALES, B ;

COPSEY, PB .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1975, 27 (06) :430-433

[7]

TAYLOR SH, 1974, INT J CLIN PHARM TH, V10, P151

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