REACTION OF OH WITH PHENYLALANINE IN NEUTRAL AQUEOUS-SOLUTION

被引：32

作者：

SOLAR, S ^{[1
]}

机构：

[1] LUDWIG BOLTZMANN INST STRAHLENCHEM,A-1090 WIEN,AUSTRIA

来源：

RADIATION PHYSICS AND CHEMISTRY | 1985年 / 26卷 / 01期

关键词：

AMINO ACIDS - Chemical Reactions;

D O I：

10.1016/0146-5724(85)90039-1

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The reactivity of OH towards phenylalanine (phala) in aqueous solutions, pH 7-8 was studied by pulse radiolysis. The site specificity of OH as well as the kinetic and spectroscopic data of the different OH adducts could be resolved by means of a semilinear optimization algorithm. The formation of benzyl-type radicals by direct abstraction of an H atom from the aniline moiety was not significant. This process together with a possible addition of OH to the ipso position of the aromatic ring was found to be 6%. MNDO calculations demonstrated that in replacing CH//3 by alanine group on the benzene ring no change takes place in the electronic charge distribution on the ring atoms as well as the energetic stabilities of the cyclohexadienyl radical isomers.

引用

页码：103 / 108

页数：6

共 31 条

[1] REACTIVITY OF AROMATIC COMPOUNDS TOWARD HYDROXYL RADICALS [J].