THE IMPORTANCE OF STEREOCHEMISTRY IN THE CLINICAL PHARMACOKINETICS OF THE 2-ARYLPROPIONIC ACID NON-STEROIDAL ANTI-INFLAMMATORY DRUGS

被引：217

作者：

HUTT, AJ ^{[1
]}

CALDWELL, J ^{[1
]}

机构：

[1] UNIV LONDON,ST MARYS HOSP,SCH MED,DEPT PHARMACOL,LONDON W2 1PG,ENGLAND

来源：

CLINICAL PHARMACOKINETICS | 1984年 / 9卷 / 04期

关键词：

D O I：

10.2165/00003088-198409040-00007

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：371 / 373

页数：3

共 20 条

[1] PHARMACOLOGICAL DIFFERENCES BETWEEN OPTICAL ISOMERS OF IBUPROFEN - EVIDENCE FOR METABOLIC INVERSION OF (-)-ISOMER
ADAMS, SS
BRESLOFF, P
MASON, CG
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1976, 28 (03) : 256 - 257
[2] BOPP RJ, 1979, DRUG METAB DISPOS, V7, P356
[3] BIOLOGICAL-ACTIVITY OF INDOPROFEN AND ITS OPTICAL ISOMERS
BUTTINONI, A
FERRARI, M
COLOMBO, M
CESERANI, R
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1983, 35 (09) : 603 - 604
[4] SEPARATION AND DETERMINATION OF NAPROXEN ENANTIOMERS IN SERUM BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
GOTO, J
GOTO, N
NAMBARA, T
[J]. JOURNAL OF CHROMATOGRAPHY, 1982, 239 (APR): : 559 - 564
[5] ANTAGONISM OF SLOW REACTING SUBSTANCE IN ANAPHYLAXIS(SRS-A) AND OTHER SPASMOGENS ON GUINEA-PIG TRACHEAL CHAIN BY HYDRATROPIC ACIDS AND THEIR EFFECTS ON ANAPHYLAXIS
GREIG, ME
GRIFFIN, RL
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (01) : 112 - 116
[6] NONSTEROIDAL ANTIINFLAMMATORY AGENTS .1. 6-SUBSTITUTED 2-NAPHTHYLACETIC ACIDS
HARRISON, IT
LEWIS, B
NELSON, P
ROOKS, W
ROSZKOWS.A
TOMOLONI.A
FRIED, JH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1970, 13 (02) : 203 - &
[7] THE METABOLIC CHIRAL INVERSION OF 2-ARYLPROPIONIC ACIDS - A NOVEL ROUTE WITH PHARMACOLOGICAL CONSEQUENCES
HUTT, AJ
CALDWELL, J
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1983, 35 (11) : 693 - 704
[8] JENNER P, 1973, DRUG METAB REV, V2, P117
[9] STEREOSPECIFIC ASSAY AND STEREOSPECIFIC DISPOSITION OF RACEMIC CARPROFEN IN RATS
KEMMERER, JM
RUBIO, FA
MCCLAIN, RM
KOECHLIN, BA
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1979, 68 (10) : 1274 - 1280
[10] INHIBITION OF PROSTAGLANDIN SYNTHASE BY PIRPROFEN - STUDIES WITH SHEEP SEMINAL-VESICLE ENZYME
KU, EC
WASVARY, JM
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 384 (02) : 360 - 368

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