A CONTROLLED-STUDY OF CAUDAL EPIDURAL INJECTIONS OF TRIAMCINOLONE PLUS PROCAINE FOR THE MANAGEMENT OF INTRACTABLE SCIATICA

被引:193
作者
BUSH, K [1 ]
HILLIER, S [1 ]
机构
[1] ROYAL FREE HOSP,DEPT RHEUMATOL,LONDON,ENGLAND
关键词
SCIATICA; CAUDAL EPIDURAL INJECTIONS; STEROID; PAIN; QUALITY OF LIFE; STRAIGHT LEG RAISE;
D O I
10.1097/00007632-199105000-00015
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The management of sciatica due to lumbar nerve root compromise remains controversial, probably because few well-controlled studies of conservative management have been performed. This preliminary study assesses the efficacy of epidural injections of 80 mg triamcinolone acetonide plus 0.5% procaine hydrochloride in saline, administered via the caudal route, in a double-blind, placebo controlled trial with 1 year follow-up. Twenty-three patients were entered into the study: 12 received treatment and 11 placebo. The active group showed significant pain relief (P = 0.02) and a significant increase in mobility (P = 0.01) at 4 weeks, which resulted in improved quality of life (P = 0.02). At 1 year, subjective and objective measures improved in both groups. The improvement was greater in the actively treated group, but only the objective assessment (straight leg raise) was statistically significant.
引用
收藏
页码:572 / 575
页数:4
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