HUMAN HERPESVIRUS-7 IS A CONSTITUTIVE INHABITANT OF ADULT HUMAN SALIVA

被引：146

作者：

WYATT, LS ^{[1
]}

FRENKEL, N ^{[1
]}

机构：

[1] NIAID,VIRAL DIS LAB,BETHESDA,MD 20892

来源：

JOURNAL OF VIROLOGY | 1992年 / 66卷 / 05期

关键词：

D O I：

10.1128/JVI.66.5.3206-3209.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We report the frequent isolation of human herpesvirus 7 from the saliva of healthy adults. Virus isolates recovered from different individuals exhibited minimal restriction enzyme polymorphism, which was mostly confined to heterogenous (het) sequences in the genome. DNAs of isolates recovered from the same individual over a period of several months showed the same characteristic het fragments, indicating the stability of the het sequences upon virus replication and shedding in vivo. In contrast to the results of previous reports, human herpesvirus 6, the causative agent of roseola infantum, could not be isolated from the saliva specimens, raising questions regarding oral transmission of human herpesvirus 6 and human herpesvirus 7 to young children.

引用

页码：3206 / 3209

页数：4

共 34 条

[1] FATAL FULMINANT-HEPATITIS IN AN INFANT WITH HUMAN HERPESVIRUS-6 INFECTION [J].